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Clostridium difficile associated diarrheaCDADhas been reported with use of nearly all antibacterial agentsincluding DURICEFcefadroxiland may range in severity from mild diarrhea to fatal colitisTreatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of Cdifficile.

NoteCulture and susceptibility tests should be initiated prior to and during therapyRenal function studies should be performed when indicated.

Descriptionwhiteopaque capsule containing white to slightly yellowish powder.

Cefadroxil is substantially excreted by the kidneyand dosage adjustment is indicated for patients with renal impairmentsee DOSAGE AND ADMINISTRATIONRenal ImpairmentBecause elderly patients are more likely to have decreased renal functioncare should be taken in dose selectionand it may be useful to monitor renal function.

Gastrointestinal side effects have included nauseavomitingdiarrheageneral abdominal discomfortand dyspepsiaPseudomembranous colitis may occur during or after treatmentRef]

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