Physicians may prescribe up to10 mg of estrace three times a day to patients suffering from breast cancer.

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Estrogens should be used with caution in individuals with severe hypocalcemia.

Estrogens increase the risk of gallbladder diseaseDiscontinue estrogen if hypercalcemiasudden partial or complete loss of visionhypertriglyceridemiaor cholestatic jaundice occursPatients dependent on thyroid hormone replacement therapy should have their thyroid function monitored in order to maintain their free thyroid hormone levels in an acceptable rangeEndometriosis may be exacerbated in women treated post-hysterectomy with estrogen-alone therapyThe addition of progestins should be considered in these patients.

The safety and efficacy of Estrace tablets in geriatric patients has not been establishedIn generaldose selection for an elderly patient should be cautioususually starting at the low end of the dosing rangereflecting the greatest frequency of decreased hepaticrenal or cardiac functionand of concomitant disease or other drug therapy.

Estrogens may increase the risk of certain types of cancerincluding cancer of the breast or uterusIf you have or had cancertalk with your healthcare provider about whether you should take Estrace.


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